The Regulation of Kainate Receptor Action (3472 words, 6 pages)
A cyclic peptide, Tyr-Lys-c-Lys-Thr-Glu(946Ala)--Val, incorporating a 946-Ala lactam side chain linker and designed to target the PDZ domains of the postsynaptic density protein 95 (PSD-95), has been synthesized and structurally characterized by NMR while free and bound to the PDZ1 domain of PSD-95. While bound, the lactam linker of the ...
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